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E-Box Element

《英文msh詞典》E-Box Element
[入口詞] E-Box Element
[主題詞] E-Box Elements
[英文釋義] DNA locations with the consensus sequence CANNTG. ENHANCER ELEMENTS (GENETICS) may contain multiple copies of this element. E-boxes play a regulatory role in the control of transcription. They bind with basic helix-loop-helix (bHLH) type TRANSCRIPTION FACTORS. Binding specificity is determined by the specific bHLH heterodimer or homodimer combination and by the specific nucleotides at the 3rd and 4th position of the E-box sequence.